The phenomenon in which imbalance in the immune system leads to a persistent, low-grade inflammatory state in the body as we age is called “inflammaging.” Because chronic inflammation in seniors slowly damages tissues and organs throughout the body without clear acute symptoms, identifying the cause and managing it systematically is extremely important.
▪️ Cellular and Immune Aging: Senescent cells that aren’t cleared from the body remain and continuously secrete inflammatory substances (SASP).
▪️ Increased Visceral Fat and Metabolic Disease: Accumulated abdominal fat promotes the secretion of inflammatory cytokines.
▪️ Gut Microbiome Imbalance: As the intestinal barrier weakens and beneficial gut bacteria decline with age, toxins enter the body more easily.
▪️ Chronic Stress and Sleep Disorders: Excessive activation of the sympathetic nervous system and cortisol imbalance trigger inflammatory responses.
▪️ Chronic Disease and Chronic Gum Inflammation: Unresolved localized inflammation, such as periodontitis or mild arthritis, can expand into systemic inflammation.
